Discovery of Novel Thanatin-like Antimicrobial Peptides from Bean Bug .

Endogenous antimicrobial peptides (AMPs) are evolutionarily ancient molecular factors of innate immunity that play a key role in host defense. The study of the diversity of animal defense peptides has important applications in the context of the growing global antimicrobial resistance. In this study using a transcriptome mining approach, we found three novel thanatin-like β-hairpin AMPs in the bean bug , named Rip-2, Rip-3, and Rip-4.