Caracteristics of women presenting with chronic histiocytic intervillositis during pregnancy: A case-control study.

Introduction: Chronic Histiocytic Intervillositis (CHI) appears to be among the most severe placental diseases. Its rarity has limited our knowledge of the women in whom it occurs.

Objective: To search for maternal characteristics linked to the existence of CHI, by first studying the current pregnancy included in the study, then their previous pregnancies.

Total alkaline phosphatase levels by gestational age in a large sample of pregnant women.

Introduction: Total alkaline phosphatase (tALP) levels rise physiologically in maternal serum during pregnancy, and excessively so in certain conditions. However, current reference values are dated, nonlinear, and based on small samples. Factors related to variation in tALP remain unexplained.

Perinatal outcome of placental massive perivillous fibrin deposition: a case-control study.

Objective: The objectives of the study are to describe the obstetric outcomes associated with massive perivillous fibrin deposition (MFD) compared with a control series and to determine if outcome differs according to the extent of fibrin deposition.

Method: Retrospective case-control study based on placentas analyzed over a consecutive 12-year period. MFD was considered severe if it extended over more than 50% of the placenta and moderate between 25% and 50%.

Chronic histiocytic intervillositis: outcome, associated diseases and treatment in a multicenter prospective study.

Unlabelled: Introduction: In this prospective multicenter study, we aimed to describe (1) the outcome of pregnancy in the case of previous chronic histiocytic intervillositis (CHI), (2) the immunological findings and associated diseases, (3) the treatments, and (4) the factors associated with pregnancy loss.

Methods: We prospectively included all patients with a prior CHI with ongoing pregnancy between 2011 and 2013.

Results: Twenty-four women (age 34±5 years) were included in this study.