Publications by authors named "Anastasia Cheremiskina"
Article Synopsis
- The SOI-FET biosensor is a promising tool for virus detection in various fields, but it faces design and technological challenges that need addressing.
- This research focuses on improving the detection process of the "antibody + antigen" complex using Poisson probability distribution to enhance accuracy in detecting target molecules.
- The study reveals unexpected sources of detection errors and emphasizes that the performance of detection depends on the number of SOI-FET biosensors present on a crystal.
Quick label-free virus screening and highly sensitive analytical tools/techniques are becoming extremely important in a pandemic. In this study, we developed a biosensing device based on the silicon nanoribbon multichannel and dielectrophoretic controlled sensors functionalized with SARS-CoV-2 spike antibodies for the use as a platform for the detection and studding of properties of viruses and their protein components. Replicatively defective viral particles based on vesicular stomatitis viruses and HIV-1 were used as carrier molecules to deliver the target SARS-CoV-2 spike S-proteins to sensory elements.
View Article and Find Full Text PDFThe detection of influenza A virions with a nanoribbon detector (NR detector) has been demonstrated. Chips for the detector have been fabricated based on silicon-on-insulator nanoribbon structures (SOI nanoribbon chip), using a complementary metal-oxide-semiconductor (CMOS)-compatible technology-by means of gas-phase etching and standard optical photolithography. The surface of the SOI nanoribbon chip contains a matrix of 10 nanoribbon (NR) sensor elements.
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