Whisker trimming during infanthood modifies the development of spike-wave discharges and behavioral sequences in IntelliCage impulsivity paradigm in adult WAG/Rij rats.

Whisker system in rats undergoes rapid development during the first postnatal weeks. Neonatal whisker trimming increases excitability in the somatosensory cortex and affects exploratory behavior at adult ages. WAG/Rij rats are genetically predisposed to develop absence seizures in adulthood, and whisker trimming during three postnatal weeks aggravates epileptic activity in these rats.

Reliance on semantic and structural heuristics in sentence comprehension across the lifespan.

People sometimes misinterpret the sentences that they read. One possible reason suggested in the literature is a race between slow bottom-up algorithmic processing and "fast and frugal" top-down heuristic processing that serves to support fast-paced communication but sometimes results in incorrect representations. Heuristic processing can be both semantic, relying on world knowledge and semantic relations between words, and structural, relying on structural economy.

Molecular Surveillance of HIV-1 Infection in Krasnoyarsk Region, Russia: Epidemiology, Phylodynamics and Phylogeography.

Background: The information about the dynamics of the viral population and migration events that affect the epidemic in different parts of the Russia is insufficient. Possibly, the huge size of the country and limited transport accessibility to certain territories may determine unique traits of the HIV-1 evolutionary history in different regions.

Objective: The aim of this study was to explore the genetic diversity of HIV-1 in the Krasnoyarsk region and reconstruct spatial-temporal dynamics of the infection in the region.