Publications by authors named "Anastasia A Tolkacheva"
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Synopsis of recent research by authors named "Anastasia A Tolkacheva"
- Anastasia A Tolkacheva's recent research primarily focuses on the functional analysis of mutations in the DNMT3A DNA methyltransferase, particularly in the context of acute myeloid leukemia (AML).
- The study emphasizes the significance of DNA methylation in maintaining genomic stability and its disruption during the progression of malignant diseases, highlighting the critical role of altered methylation patterns.
- Notably, the R882H mutation of DNMT3A has been identified as the most prevalent among AML patients, underscoring the importance of targeted investigations into this specific mutation for understanding disease mechanisms.
