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Publications by authors named "Anastasia A Goncharova"

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The Gender-Specific Association of DRD2 Polymorphism with Metabolic Syndrome in Patients with Schizophrenia.
Diana Z Paderina Anastasiia S Boiko Ivan V Pozhidaev Irina A Mednova Anastasia A Goncharova

Genes (Basel)

July 2022

Article Synopsis
  • Metabolic syndrome is common among schizophrenia patients on long-term antipsychotic treatment, which can result from the effects of dopamine D2 receptors.
  • The study analyzed 517 schizophrenia patients in Siberia, focusing on two specific genetic variations in the DRD2 gene and their link to metabolic syndrome.
  • Findings suggest that a particular variation (rs1799732) is associated with drug-induced metabolic syndrome in women, pointing to the potential for targeted genetic treatments to improve patient outcomes.
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Comparative Characteristics of the Metabolic Syndrome Prevalence in Patients With Schizophrenia in Three Western Siberia Psychiatric Hospitals.
Elena G Kornetova Alexander N Kornetov Irina A Mednova Anastasia A Goncharova Valeria I Gerasimova

Front Psychiatry

July 2021

The purpose of this study was to compare the prevalence of MetS and the associated sociodemographic, clinical, and pharmacotherapeutic characteristics of patients with schizophrenia in three psychiatric hospitals in the West Siberian region. Patients with a clinical diagnosis of schizophrenia (ICD-10: F20) and an age between 18 and 60 years were included in the study after giving informed consent. Metabolic syndrome was diagnosed according to the International Diabetes Federation criteria.

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Synopsis of recent research by authors named "Anastasia A Goncharova"

  • - Anastasia A Goncharova's recent research focuses on the relationship between metabolic syndrome and schizophrenia, particularly investigating how genetic factors such as DRD2 polymorphisms influence this association in patients undergoing long-term antipsychotic treatment
  • - Her 2022 study found a significant gender-specific association between DRD2 polymorphisms and the prevalence of metabolic syndrome in schizophrenia patients, highlighting the role of dopamine D2 receptors in both the efficacy and side effects of antipsychotic therapy
  • - In a 2021 comparative study, Goncharova examined metabolic syndrome prevalence among schizophrenia patients in three psychiatric hospitals in Western Siberia, revealing important sociodemographic and clinical characteristics tied to the condition, which underscores the public health implications of metabolic syndrome in this population

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