Publications by authors named "Anas Zayed"
Background: Hepatocellular carcinoma (HCC) is a significant health problem associated with several risk factors, increasingly driven by non-alcoholic steatohepatitis and metabolic syndrome. This association poses a challenge for the primary treatments of HCC, which may include immune checkpoint inhibitors and vascular endothelial growth factor inhibitors, due to their potential cardiotoxic effect. Therefore, it is imperative to balance the therapeutic effects of these agents with their potential cardiovascular adverse events.
View Article and Find Full Text PDFBackground: Cyclin-dependent kinase (CDK) 4/6 inhibitors have revolutionized the treatment landscape of hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2 -) metastatic breast cancer (MBC). Here, we present the real-world clinical outcomes and toxicity data of patients treated at a single cancer center.
Methods: A retrospective analysis was conducted on patients with HR+/HER2- MBC treated with ribociclib plus endocrine therapy (ET).
Clinical Characteristics and Outcomes of CML in Adolescents and Young Adults.
Clin Lymphoma Myeloma Leuk
October 2024
Article Synopsis
- * The findings revealed that AYAs had higher initial disease severity but showed similar responses to treatment with tyrosine kinase inhibitors (TKIs) as older patients.
- * Although AYAs experienced a shorter event-free survival (EFS), their overall survival (OS) rates were comparable to those of older adults, indicating the need for more research into the unique biology of CML in younger patients.