Publications by authors named "Anargyros Bakopoulos"
The incidence of T4b esophageal cancer with aortic invasion but without distant metastasis is estimated to be between 3.8% and 4.6% of all esophageal cancer cases.
View Article and Find Full Text PDFArticle Synopsis
- Mesh placement is the standard treatment for inguinal hernias using either open surgery or the TAPP approach, both of which are generally safe but can lead to rare complications like visceral injuries.
- Two male patients experienced serious issues years after surgery, including mesh erosion and the development of mesh-enterocutaneous fistulas, requiring extensive surgical interventions such as colectomy and colostomy.
- Clinicians should be vigilant in diagnosing possible intrabdominal complications in patients with inguinal region abscesses and be prepared for surgical management in symptomatic cases.
Article Synopsis
- Thoracobiliary fistula (TBF) is a rare condition in children characterized by a connection between the bronchial and biliary trees, primarily presenting with symptoms like bilioptysis, dyspnea, and cough.
- A review of 43 studies revealed 48 TBF cases, with the left hepatic duct being the most commonly involved site, and most patients required surgical management.
- While surgeries like fistulectomy and lung resection were common, complications arose in 35.4% of cases, with a mortality rate of 6.3%, indicating TBF's serious nature stemming mainly from congenital issues.
: Encouraging data have been reported from referral centers following gastrointestinal cancer surgery. Our goal was to retrospectively review patient outcomes following gastrectomy for gastric or gastroesophageal junction (GEJ) cancer at a high-volume unit of the University of Athens. : The enrollment period was from June 2003 to September 2018.
View Article and Find Full Text PDFArticle Synopsis
- SADF (Secondary Aortoduodenal Fistulae) are serious complications arising from aortic surgeries, with limited data on their associated risks and outcomes.
- A review of existing literature included 189 patients treated for SADF, highlighting varied surgical interventions like aortic graft excision and bowel repairs, but showed no significant difference in mortality rates based on the type of surgery performed.
- Omentoplasty, a procedure involving the addition of abdominal tissue, was found to significantly lower mortality risk, indicating that comprehensive management of both aortic and duodenal issues is crucial for better patient outcomes.
Inflammatory diseases of the pancreas or pancreatic trauma result in ductal cell disruption, which in turn may lead to leakage of pancreatic fluid, mostly in the retroperitoneal space. Pancreatopleural fistulas are uncommonly encountered following pancreatic injury; however, they often prove a difficult problem to manage. Herein, we present a rare case of a 68-year-old male suffering from a pancreaticopleural fistula (PF) between the pancreatic tail and the left pleural space one year following splenectomy for trauma.
View Article and Find Full Text PDFThe co-occurrence of abdominal aortic aneurysm (AAA) and colorectal malignancy creates a significant surgical dilemma over which entity should be addressed first. A 73-year-old male was referred to our hospital due to a painful pulsatile abdominal mass. Computed tomographic angiography revealed an infrarenal aortic aneurysm measuring 5.
View Article and Find Full Text PDFGallstone ileus is an uncommon complication of cholelithiasis and occurs when a gallstone migrates through a cholecystoenteric fistula and impacts within the gastrointestinal tract. Surgical intervention remains the treatment of choice, which consists of a full-thickness incision of the visceral wall and removal of the impacted gallstone. In this paper we present the treatment approach of 6 cases of gallstone ileus in octogenarians.
View Article and Find Full Text PDFBackground: Thoracopancreatic fistulae are a rare complication of chronic pancreatitis. The aim of the present study is to evaluate potential risk factors for endoscopic treatment failure and explore the safety of surgery when utilized either upfront or as a "bail-out" procedure after failed endoscopic treatment.
Method: A comprehensive literature search was conducted on the MedLine, Scopus, Embase, and Web of Knowledge databases for cases of thoracopancreatic fistulae.
The Immunology of Hepatocellular Carcinoma.
Vaccines (Basel)
October 2021
Article Synopsis
- Liver cancer, specifically hepatocellular carcinoma (HCC), is a significant global health issue, ranked as the third leading cause of cancer death, with surgical options like resection and transplantation not suitable for many patients.
- Locoregional therapies provide limited palliative benefits, leading to increased interest in novel systemic treatments such as immunotherapy, which targets the immune response against cancer cells.
- This review focuses on the potential of immunomodulating therapies, including vaccines and immune checkpoint inhibitors, to improve treatment outcomes and survival rates in patients with advanced HCC.
Background: Morgagni's hernia (MH) is defined by the protrusion of abdominal viscera through an anterior retrosternal diaphragmatic defect. The objective of this study was to systematically review current literature on MHs in adult population and assess their clinical characteristics and therapeutic approach.
Methods: PubMed and Cochrane bibliographical databases were searched (last search: 15 January 2021) for studies concerning MHs.
Pneumothorax as a rare complication during laparoscopic total extra-peritoneal inguinal hernia repair: A case report and review of the literature.
J Minim Access Surg
January 2021
Totally extra-peritoneal (TEP) and trans-abdominal pre-peritoneal repair are the two most commonly performed types of laparoscopic hernia repair procedures. Herein, we present a rare case of pneumothorax and pneumomediastinum that ensued during a TEP inguinal hernia repair. A 73-year-old man presented for elective laparoscopic right-sided hernia repair.
View Article and Find Full Text PDFArticle Synopsis
- The study reviews evidence on intestinal erosion caused by mesh used in inguinal hernia repairs and investigates factors affecting symptom timing.
- Out of 54 cases examined, 23% showed early symptoms (within 6 months) and 67% showed late symptoms, with late cases linked to more mesh erosion incidents.
- Early presentations were often tied to minimally invasive surgeries and more acute intestinal obstruction symptoms, while late presentations required higher rates of bowel resection and were typically associated with open procedures.
The aim of this study is to describe outcomes of esophageal cancer surgery in a quaternary upper gastrointestinal (GI) center in Athens during the era of the Greek financial crisis. We performed a retrospective analysis of patients that underwent esophagectomy for esophageal or gastroesophageal junction (GEJ) cancer at an upper GI unit of the University of Athens, during the period January 2004-June 2019. Time-to-event analyses were performed to explore trends in survival and recurrence.
View Article and Find Full Text PDFArticle Synopsis
- ALPPS (Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy) is a groundbreaking surgical technique that allows for the resection of liver tumors previously deemed unresectable by promoting rapid liver growth.
- A systematic review analyzed 28 studies involving 136 patients with primary liver cancer who underwent ALPPS, noting a high R0 resection rate of approximately 97.24% and a 30-day mortality rate of 9.55%.
- Oncological outcomes showed a median disease-free survival of 6 months and overall survival of 11 months, with a 36% recurrence rate during a median follow-up of 10 months.
Background: Neoplasms arising in the esophagus may coexist with other solid organ or gastrointestinal tract neoplasms in 6% to 15% of patients. Resection of both tumors synchronously or in a staged procedure provides the best chances for long-term survival. Synchronous resection of both esophageal and second primary malignancy may be feasible in a subset of patients; however, literature on this topic remains rather scarce.
View Article and Find Full Text PDFPerioperative Management of Antiplatelet Therapy in Patients With History of Coronary Artery Disease Undergoing Surgery for Esophageal Cancer: A Single-center Experience.
In Vivo
June 2019
Aim: To present the experience of the upper Gastrointestinal Unit of the Surgical Department of National and Kapodistrian University of Athens in order to inform surgeons of the exact harms and benefits associated with their decisions concerning management of antiplatelet therapy.
Materials And Methods: This was a single-center study of patients who underwent surgery for esophageal cancer and had concomitant coronary artery disease from 1/1/2005 to 31/7/2017. Patients were divided into two cohorts based on when their antiplatelet therapy was stopped (<7 vs.
Endoscopic Retrograde Cholangiopancreatography for Ampullary Carcinomas: Friend or Foe?
J Long Term Eff Med Implants
January 2019
Article Synopsis
- The effectiveness of preoperative ERCP for ampullary carcinomas is questioned due to the risk of complications.
- A case study involving a 59-year-old male showed that ERCP led to serious issues, including bleeding and perforation after the procedure.
- The findings suggest that performing procedures like ERCP before surgery might negatively impact patient outcomes.
Background: Injuries to segmental or aberrant bile ducts are encountered less commonly than their major bile duct counterparts and present a unique diagnostic and therapeutic challenge, since the nature of this injury involves a transected bile duct that loses its communication with the main ductal system. In this systematic review, we aim to pool available data on this particular type of biliary injury in an effort to outline available diagnostic and therapeutic modalities and evaluate their efficacy.
Materials And Methods: An extensive literature search was performed on MEDLINE, Scopus, and Web of Science to identify isolated segmental or aberrant bile duct injuries.
Article Synopsis
- HCC rupture is a serious condition linked to blood vessel problems and clotting issues, causing challenges in emergency treatment.
- A successful case was reported of a 66-year-old woman who underwent emergency transarterial embolization (TAE) for her ruptured HCC, showing tumor shrinkage as a positive outcome.
- The findings suggest TAE followed by surgery could be effective for certain patients, highlighting the need for more research to create tailored treatment guidelines based on liver function and patient health.
Article Synopsis
- Clear cell tumor of the lung (CCTL) is an extremely rare type of tumor, with only about 50 documented cases, often misdiagnosed due to lack of awareness.
- It is characterized by high glycogen content, giving it a "sugar tumor" nickname, and is typically diagnosed through fine needle aspiration (FNA) cytology and pathological examination.
- The case reported illustrates that recognizing its specific cytomorphologic features and immunochemistry results can lead to accurate diagnosis and potentially prevent unnecessary lung surgeries, allowing for more conservative treatment options.
Article Synopsis
- Sepsis significantly affects blood cell counts, showing decreased white blood cells (WBCs) and lymphocytes across all sepsis groups compared to controls.
- The levels of certain biochemical markers, such as creatinine and interleukins (IL-10 and IL-6), were notably elevated in the sepsis groups, indicating an inflammatory response.
- Toll-like receptors (TLRs) 2, 3, 4, and 7 showed increased expression in the lungs of sepsis models, suggesting their role in respiratory system involvement during sepsis and serving as a potential severity indicator.