Publications by authors named "Ananya S Iyyangar"
Hyperglycemia Is Associated With Computed Tomography Perfusion Core Volume Underestimation in Patients With Acute Ischemic Stroke With Large-Vessel Occlusion.
Arash Niktabe Juan Carlos Martinez-Gutierrez Sergio Salazar-Marioni Rania Abdelkhaleq Juan Carlos Rodriguez Quintero Ananya S Iyyangar
Stroke Vasc Interv Neurol
July 2024
Background: CT Perfusion (CTP) predictions of infarct core play an important role in the determination of treatment eligibility in large vessel occlusion (LVO) acute ischemic stroke (AIS). Prior studies have demonstrated that blood glucose can affect cerebral blood flow (CBF). Here we examine the influence of acute and chronic hyperglycemia on CTP estimations of infarct core.
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- The study investigates how using automated interpretations of CT scans and secure messaging can speed up the process of endovascular stroke therapy (EVT) for large vessel occlusion (LVO) strokes in hospitals.
- Conducted at four comprehensive stroke centers in Houston, Texas, the trial involved 443 patients with LVO strokes and aimed to reduce critical time metrics such as door-to-groin (DTG) time after implementing AI technology.
- The primary outcome measured was the impact on DTG time using statistical models, while secondary outcomes included the time from hospital arrival to treatment and patient recovery metrics at 90 days.
Article Synopsis
- Prehospital routing of patients with large vessel occlusion (LVO) acute ischemic stroke (AIS) to comprehensive stroke centers (CSCs) can potentially improve clinical outcomes, and this study investigates factors influencing such routing, particularly focusing on distance, stroke severity, and sex.
- The study analyzed 503 patients in the greater Houston area, revealing that while 82% were routed to CSCs, women were 9% less likely to be routed compared to men, despite presenting with more severe stroke symptoms and similar distances to CSCs.
- Findings indicate that women were older and had higher stroke severity scores; further research is necessary to understand the reasons behind the lower routing rates for women.