Publications by authors named "Ananthram Shetty"
The presence of mesenchymal progenitor cells (MPCs) in rheumatoid arthritis (RA) articular cartilage is sparsely investigated largely owing to the persistent pathogenic disease condition and lack of specific biomarkers. Considering the recent advancements for potential cell-based therapies in immunomodulatory diseases, such as RA, this in vitro study was aimed at investigating the cellular, molecular, and differentiation characteristics of human RA cartilage-derived MPCs. Articular cartilage fragments from RA patients were obtained for the isolation of MPCs and characterization of their cellular and biological properties, cytogenetic stability, pluripotency, and plasticity.
View Article and Find Full Text PDFObjective: A novel single-stage approach using arthroscopic microdrilling and atelocollagen/fibrin-gel application is employed for cartilage repair of the knee. The purpose of our study was to investigate the morphological and biochemical MRI outcome after this technique.
Materials And Methods: A retrospective case series of ten patients (mean age 45 years) with symptomatic chondral defects in the knee who were treated arthroscopically with microdrilling and atelocollagen application was analyzed.
Article Synopsis
- A study evaluated the long-term survival and effectiveness of 112 JRI hydroxyapatite ceramic-coated acetabular components after at least 13 years of follow-up.
- Clinical assessments showed significant improvement in patient scores for pain, motion, and walking ability post-surgery compared to preoperative levels.
- The survival rate for the components was 99% at the 13-year mark, with no cases of loosening, migration, or the need for revision reported.