Publications by authors named "Anantha P Reddy"
Chem Res Toxicol
May 2003
Article Synopsis
- 1,3-Butadiene is a potential carcinogen that gets metabolized into a highly mutagenic compound called diepoxybutane (DEB), which necessitates the identification of a specific biomarker for studying its toxic effects.
- A new biomarker, pyr-V, is formed when DEB interacts with hemoglobin, and the study aimed to create a precise assay to measure this biomarker.
- The researchers synthesized various forms of a cyclic Val adduct linked to an oligopeptide sequence to develop antibodies and establish a quantification method for measuring DEB's effects.
