Publications by authors named "Anania C"

Cow's milk allergy (CMA) is the most common food allergy among children. An oral food challenge (OFC) remains a mainstay of the diagnosis of CMA, especially for the non-IgE-mediated type; however, this test can be risky and time-consuming. Hence, there is a need to identify biomarkers.

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: Postoperative cerebrospinal fluid (CSF) fistulas remain a significant concern in spinal neurosurgery, particularly following dural closure. The incidence of dural tears during spinal surgery is estimated between 1.6% and 10%.

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Background: Angioedema is a condition marked by sudden, intense swelling of the subcutaneous and submucosal tissues, typically associated with hypersensitivity reactions, genetic mutations, or reactions to medications. It can also result from contact with allergens such as nickel, leading to dermatitis.

Case Presentation: A 12-year-old girl presented at our Pediatric Immunology and Allergology service with recurrent labial angioedema for over a year, linked to the consumption of legumes and tomatoes, and following the use of a metal flute.

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While Trisomy X syndrome is typically characterized by developmental and cognitive variations, it is not commonly associated with immunodeficiencies. We report the unique case of a 6-year-old girl with Trisomy X presenting with selective IgA deficiency, challenging the conventional understanding of this chromosomal condition. The patient exhibited recurrent respiratory infections and gastrointestinal symptoms, evaluated in the context of her genetic background of Trisomy X and significantly low levels of IgA (0.

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Article Synopsis
  • Food allergy (FA) affects around 6-8% of young children, with tree nut and peanut allergies being major causes of severe allergic reactions (anaphylaxis).
  • The oral food challenge (OFC) is the most reliable method for diagnosing food allergies, while skin prick tests (SPTs) and serum specific IgE (sIgE) tests are also commonly used.
  • Evidence on the predictive value of SPTs and sIgE regarding OFC outcomes is inconsistent, indicating that while these tests can sometimes provide insights, OFC is still the definitive diagnosis method for food allergies.
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Article Synopsis
  • No existing algorithms guide surgical strategies in complex cases of degenerative cervical myelopathy (DCM), prompting the creation of the Cervical Surgical Score (CSS) to identify and suggest treatment options for complex cases.
  • The CSS was developed through multidisciplinary discussions and considers eight parameters related to cervical pathology and clinical myelopathy, with a study involving 100 patients undergoing surgery and comparing surgical recommendations from the CSS and a standard outpatient approach.
  • Results indicated that CSS effectively identified cases in a "grey zone" for surgical approach options, leading to changes in planned surgeries for nearly 43% of those cases, with 62% of patients showing improved clinical outcomes.
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Food allergy (FA) affects approximately 6-8% of children worldwide causing a significant impact on the quality of life of children and their families. In past years, the possible role of weaning in the development of FA has been studied. According to recent studies, this is still controversial and influenced by several factors, such as the type of food, the age at food introduction and family history.

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Objective: The development of specific clinical and neurological symptoms and radiological degeneration affecting the segment adjacent to a spinal arthrodesis comprise the framework of adjacent-level syndrome. Through the analysis of a large surgical series, this study aimed to identify possible demographic, clinical, radiological, and surgical risk factors involved in the development of adjacent-level syndrome.

Methods: A single-center retrospective analysis of adult patients undergoing lumbar fusion procedures between January 2014 and December 2018 was performed.

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allergy is an emerging pathological condition in both general and pediatric populations with a wide range of symptoms linked to variable molecular patterns, justifying systemic and cross-reactions with other allergens (i.e., latex, pollen, and fruit).

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Background: We followed the effects of a new SCIT with a chemically polymerized allergen Alt a1, evaluating the trend of clinical and functional parameters in an observational-prospective study.

Methods: 42 children with AR and intermittent asthma sensitized to A.A.

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Cervical spondylotic myelopathy (CSM) is a progressively growing pathology to afford by a spinal surgeon due to the aging of the population, associated with better treatment management and the best diagnosis and treatment solutions are greatly discussed. Nowadays that scientific literature is progressively increasing to identify the gold standard in diagnosis and treatment can be very challenging. This is particularly evident in spinal surgery with many different indications not only in different countries but also in the same local reality.

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