Publications by authors named "Anandapadmanabhan Reghu"
Background: The merits of classifying the heterogeneous group of essential tremors into essential tremor (ET) and essential tremor plus (ETP) are debated.
Objectives: We studied the electrophysiological and spiral characteristics of tremor in ET and ETP.
Methods: We reviewed standardized videos from a tremor database and clinically classified patients into ET, ETP, or dystonic tremor (DT).
Article Synopsis
- Neuropathic Tremor (NT) can occur in patients recovering from Guillain-Barré Syndrome (GBS), characterized by a postural/kinetic tremor of the upper extremities.
- NT in this context features a fine, fast, slightly jerky tremor with frequencies between 8 to 10 Hz, often accompanied by dystonic posturing and overflow movements.
- Electrophysiological evaluations suggest that NT involves a central oscillator mechanism, potentially linked to cerebellar dysfunction due to impaired sensorimotor feedback during recovery from GBS.
Article Synopsis
- The study explores how Parkinson's disease affects various aspects of social cognition in Indian patients, highlighting impairments in understanding social situations compared to healthy volunteers.
- Using the SOCRATIS tool, researchers assessed theory of mind, attributional biases, and social cue perception in 52 PD patients and 31 healthy volunteers.
- Results showed that PD patients struggled more with social cognition and had a tendency to blame external factors for negative events, but these deficits did not correlate with their overall quality of life.
Importance: There is an unmet need for safe and efficacious treatments for upper-extremity dystonic tremor (DT). To date, only uncontrolled retrospective case series have reported the effect of botulinum neurotoxin (BoNT) injections on upper-extremity DT.
Objective: To assess the effect of BoNT injections on tremor in patients with upper-extremity DT.