Inhibitory effect of a resin coat-containing prereacted glass fillers on the enamel demineralization of the primary teeth: An pilot study.

Background: With an increasing interest in preventive strategies, pedodontics research is now more focused on developing newer materials and techniques to coat the primary teeth to prevent onset of new carious lesions.

Aim: The aim of this study is to evaluate the inhibitory effect of prereacted glass (PRG) filler-containing resin coat on enamel demineralization of the primary teeth.

Subjects And Methods: Eight de-rooted primary caries-free teeth sectioned into 4 mm × 4 mm were divided into either experimental group which received the PRG barrier coat or control group which was left uncoated.

Effect of 1, 25 dihydroxyvitamin D(3) on matrix metalloproteinases MMP-7, MMP-9 and the inhibitor TIMP-1 in pulmonary tuberculosis.

Matrix metalloproteinases (MMPs) play a vital role in the pathogenesis of several inflammatory diseases including tuberculosis through tissue remodeling. 1, 25(OH)(2)D(3) has several well recognized biological functions including suppression of MMP production. The influence of 1, 25(OH)(2)D(3) on MMP-7, MMP-9 and tissue inhibitor of metalloproteinase-1 (TIMP-1), production was studied in 43 pulmonary tuberculosis (PTB) patients and 44 healthy controls (HC).