Publications by authors named "Anand Maligireddy"

Article Synopsis
  • Tricuspid regurgitation (TR) is a serious condition linked to long-term health issues, including severe right heart failure, but newer less invasive treatments like transcatheter valve interventions (TTVI) are gaining attention.
  • A study analyzing over 98,000 tricuspid valve procedures from 2011 to 2020 revealed trends in intervention types, showing a rise in TTVI and a decline in traditional surgical options.
  • Findings indicate demographic factors like age and race affect procedure choice and outcomes, with surgical interventions showing higher mortality rates; further research is needed to understand the causes of these evolving trends in treatment results.
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Purpose: This study aimed to analyze two decades of consecutive mortality data to investigate cardiovascular deaths in Systemic Lupus Erythematosus (SLE) across the United States (US), identifying patterns and disparities in mortality rates.

Methods: A retrospective analysis was conducted using mortality data from the CDC WONDER database spanning 1999-2020. ICD-10 codes for diseases of circulatory system (I00-I99) and for SLE (M32) were used to identify cardiovascular-related deaths in SLE among adults aged 25 years and older at the time of death.

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Pulmonary embolism (PE) is a life-threatening condition with increasing hospital admissions. Prompt identification and treatment of PE patients with hemodynamic collapse are essential. Conflicting recommendations and weak evidence hinder effective management of PE, resulting in unchanged mortality rates despite advancements in therapies.

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Pulmonary hypertension (PH) disproportionately affects women, presenting challenges during pregnancy. Historically, patients with PH are advised to avoid pregnancy; however, recent reports have indicated that the incidence of adverse events in pregnant patients with PH may be lower than previously reported. We conducted a retrospective cohort study in pregnant patients with PH using the National Readmission Database from January 1, 2016, to December 31, 2020.

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Balloon pulmonary angioplasty (BPA) was first described in 2001 and now has evolved into a class I indication for inoperable or residual chronic thromboembolic pulmonary hypertension. This review article aims to describe evidence from studies performed at various pulmonary hypertension (PH) centers across the globe, to better understand the role of BPA in chronic thromboembolic pulmonary disease with and without PH. Additionally, we hope to highlight innovations and the ever-changing safety and efficacy profile of BPA.

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Intravascular lithotripsy can be used as an effective therapy for lesion preparation in severely calcified lesions. The mechanism, as shown by optical coherence tomography, is calcium fractures. The aforementioned modification is performed with minimal risk of perforation, no-reflow and a low incidence of flow-limiting dissection and myocardial infarctions.

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• Aortic valve fenestrations should be considered as a rare cause of AR. • Timing of surgical intervention for chronic asymptomatic severe AR warrants serial TTE. • TTE measurements of LV dimensions and EF help decide timing of aortic valve repair.

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Article Synopsis
  • - Pulmonary hypertension (PH) is common in India but faces significant care delivery challenges due to the country's lower middle-income status, with physicians noting inconsistent practices and a lack of dedicated programs for managing the condition.
  • - Interviews with doctors revealed that frequent causes of PH included rheumatic mitral valve disease, coronary artery disease, and congenital heart disease, but diagnostic procedures and treatment protocols were often insufficient or varied.
  • - Major barriers to effective PH management include limited physician training, absence of tailored treatment guidelines for lower middle-income countries, and socioeconomic factors affecting patient access to care and understanding of the disease.
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Arterial spin labeling (ASL) is a functional magnetic resonance imaging (fMRI) technique that uses water in arterial blood as a tracer to map an area of interest where the intravascular and extravascular compartments exchange. Our review article focuses primarily on the role of ASL fMRI in assessing perfusion impairment in renal allografts in order to take appropriate steps to eliminate the cause of perfusion impairment at an early stage, thereby extending graft life. The study also highlights various other fMRI techniques that are used to analyze other parameters that affect kidney transplants both acutely and chronically.

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Gastroparesis or gastric stasis is the delayed transit of the ingested contents through the stomach in the absence of mechanical obstruction. It can have multiple etiologies, most commonly idiopathic (ID) and diabetic (DM). Gastroparesis can cause significant distress to patients as it leads to symptoms like intractable nausea and vomiting, weight loss, abdominal bloating, early satiety, etc.

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