Publications by authors named "Anand Kumar Tengli"
Article Synopsis
- Thirteen isopropyl chalcones were synthesized and tested for their ability to inhibit monoamine oxidase (MAO), finding that all compounds were more effective against MAO-B than MAO-A.
- The most potent inhibitor of MAO-B was identified as having an IC value of 0.032 μM, showing high selectivity over MAO-A, while another compound was the strongest inhibitor for MAO-A at 0.310 μM.
- Kinetic studies indicated that specific compounds exhibited reversible inhibition for both MAO-A and MAO-B, highlighting their potential use in treating Parkinson's disease.
