Synthesis of cefixime loaded PCL/HPMC blend nanoparticles: a controlled release study and anti-bacterial evaluation.

Aim: To enhance cefixime's effectiveness and address drug delivery challenges like concentration at the site, dose, and time, present study investigated the impact of polymer blends on cefixime's release profile.

Methods: Cefixime-loaded nanoparticles were prepared via a modified solvent evaporation method, forming a W/O/W double emulsion. Characterisation included FT-IR, zeta potential, TGA, TEM, and XRD, with in vitro studies and kinetic models used to analyse the release mechanism.

Age determination in children by orthopantomograph and lateral cephalogram: A comparative digital study.

Background And Aims: The assessment of age is useful in forensic medicine and forensic odontology and in treatment planning in various branch of dentistry. The aim of study is comparative evaluation and assessment of applicability of Demirjian's method, Willem's method of dental age (DA) estimation, and Maria de Paula Caldas's method of skeletal age estimation for children aged 9-16 years.

Materials And Methods: A total of 140 individuals (70 females and 70 males) between the age group of 9-16 years were enrolled.