Voxel-Based Lesion Analysis of Ideomotor Apraxia.

Ideomotor apraxia is a cognitive disorder most often resulting from acquired brain lesions (i.e., strokes or tumors).

Action and object processing in brain-injured speakers of Chinese.

Objective: To see whether action and object processing across different tasks and modalities differs in brain-injured speakers of Chinese with varying fluency and lesion locations within the left hemisphere.

Method: Words and pictures representing actions and objects were presented to a group of 33 participants whose native and/or dominant language was Mandarin Chinese: 23 patients with left-hemisphere lesions due to stroke and 10 language-, age- and education-matched healthy control participants. A set of 120 stimulus items was presented to each participant in three different forms: as black and white line drawings (for picture-naming), as written words (for reading) and as aurally presented words (for word repetition).

What do brain lesions tell us about theories of embodied semantics and the human mirror neuron system?

Recent work has been mixed with respect to the notion of embodied semantics, which suggests that processing linguistic stimuli referring to motor-related concepts recruits the same sensorimotor regions of cortex involved in the execution and observation of motor acts or the objects associated with those acts. In this study, we asked whether lesions to key sensorimotor regions would preferentially impact the comprehension of stimuli associated with the use of the hand, mouth or foot. Twenty-seven patients with left-hemisphere strokes and 10 age- and education-matched controls were presented with pictures and words representing objects and actions typically associated with the use of the hand, mouth, foot or no body part at all (i.

Timed action and object naming.

Factors affecting object and action naming were compared in a timed picture-naming paradigm, for drawings of 520 objects and 275 actions, named by adult native speakers of English. Massive differences between object and action naming were observed for all dependent variables, and theoretically relevant differences emerged in the variables that predict retrieval of nouns vs. verbs in this task.