Publications by authors named "Anais Rat"
Telomere shortening ultimately causes replicative senescence. However, identifying the mechanisms driving replicative senescence in cell populations is challenging due to the heterogeneity of telomere lengths and the asynchrony of senescence onset. Here, we present a mathematical model of telomere shortening and replicative senescence in Saccharomyces cerevisiae which is quantitatively calibrated and validated using data of telomerase-deficient single cells.
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- The study investigates the genetic resistance of pea plants to a damaging soilborne pathogen in France, focusing on breeding resistant varieties by analyzing quantitative trait loci (QTL).
- It combines new QTL mapping in advanced backcross populations with previous studies and integrates a genome-wide association study (GWAS) to identify resistance markers.
- Ultimately, the research identifies 29 resistance-associated SNPs and 171 resistance QTL, confirming existing genetic regions and highlighting a rich diversity of resistance haplotypes for future breeding efforts.