Publications by authors named "Anais Briant"

Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for an important mortality rate worldwide. We aimed to evaluate the actual imputability of SARS-CoV-2 on the mortality rate associated with SARS-CoV-2-related illnesses in the pediatric intensive care unit (PICU). Secondary objectives were to identify risk factors for death.

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Introduction: To analyze the safety and long-term result of bariatric surgery in patients with psychiatric disorders.

Material And Methods: From January 2009 to December 2018, n = 961 patients underwent bariatric surgery in a tertiary center. Among them, two groups of patients were created: a group of patients with psychiatric disorders (PG) and a group without psychiatric disorders (CG), using a propensity score matched (PSM).

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Background: Sarcopenia diagnosis is partly based on handgrip strength (HGS) assessment. The gold-standard dynamometer for this measurement is the Jamar. The electronic Gripwise is a smaller and lighter one, and its measurements are correlated with the Jamar's in laboratory tests.

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Background: Distal anterior cerebral aneurysm (DACA) represents 4% of intracranial aneurysms. Two treatment modalities are available: microsurgery and endovascular therapy (EVT).

Objective: To compare the results between microsurgery and EVT in a modern French cohort.

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Article Synopsis
  • Postoperative atrial fibrillation (PoAF) affects about 30% of patients after cardiac surgery, with two main management strategies: rate control using beta-blockers or rhythm control using amiodarone, but evidence for one being superior to the other is lacking.
  • A new study, the FAAC trial, aims to compare landiolol, a new beta-blocker, with amiodarone to see if landiolol can achieve a higher rate of restoring normal heart rhythm within 48 hours after PoAF starts.
  • This randomized controlled trial is designed to include 350 patients over two years and will help determine if landiolol can significantly improve recovery from PoAF following cardiac procedures.
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Article Synopsis
  • Ruptured middle cerebral artery aneurysms (MCAa) can cause serious brain bleeding (intracerebral hematoma), and the study aimed to compare the outcomes of two treatments: microsurgery (clipping) and endovascular therapy (EVT).
  • The research involved 162 adult patients who needed evacuation of intracerebral hematoma across nine hospitals in France, analyzing factors linked to recovery using a standard scale (modified Rankin scale) after six months.
  • Results showed that clipping was associated with better functional outcomes (30% poor outcome rate) compared to EVT (76% poor outcome rate), potentially due to longer delays in treatment for the EVT group.
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Background: Bariatric surgery is known to improve stress urinary incontinence (SUI) and overactive bladder disorders (OAB). However, there is little long-term follow-up in the literature.

Objective: To determine the long-term effect of bariatric procedures on SUI and OAB and their impact on quality of life, we applied the ICIQ and USP questionnaires.

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Introduction: Natalizumab, a therapy for relapsing-remitting multiple sclerosis (RRMS), is associated with a risk of progressive multifocal leukoencephalopathy (PML). Over the last several years, practitioners have used off-label extended interval dosing (EID) of natalizumab to reduce PML risk, despite the absence of a large-scale efficacy evaluation.

Methods: We conducted a retrospective, multicenter cohort study among adults with RRMS receiving stable standard interval dosing (SID), defined as a ≥ 12-month consecutive period of ≥ 11 natalizumab infusions/year in France.

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Background: The anatomic site for central venous catheter insertion influences the risk of central venous catheter-related intravascular complications. We developed and validated a predictive score of required catheter dwell time to identify critically ill patients at higher risk of intravascular complications.

Methods: We retrospectively conducted a cohort study from three multicenter randomized controlled trials enrolling consecutive patients requiring central venous catheterization.

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Article Synopsis
  • The study analyzed the prevalence and impact of anemia in children diagnosed with chronic myeloid leukemia (CML), highlighting that 81% of 430 patients had anemia at diagnosis, with many experiencing moderate to severe cases.
  • Moderate and severe anemia were linked to younger age, symptoms like fatigue, and higher blood cell counts, leading to delays in effective treatment response with imatinib.
  • Although anemia was common and influenced treatment outcomes, it did not significantly affect overall survival rates in pediatric CML patients.
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Purpose: Intravenous maintenance fluid therapy (IV-MFT) prescribing in acute and critically ill children is very variable among pediatric health care professionals. In order to provide up to date IV-MFT guidelines, the European Society of Pediatric and Neonatal Intensive Care (ESPNIC) undertook a systematic review to answer the following five main questions about IV-MFT: (i) the indications for use (ii) the role of isotonic fluid (iii) the role of balanced solutions (iv) IV fluid composition (calcium, magnesium, potassium, glucose and micronutrients) and v) and the optimal amount of fluid.

Methods: A multidisciplinary expert group within ESPNIC conducted this systematic review using the Scottish Intercollegiate Guidelines Network (SIGN) grading method.

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Objective: Middle cerebral artery aneurysms (MCAAs) have been considered good candidates for microsurgery. Our objective was to evaluate the risk of complications and the risk factors for complications with microsurgical treatment of MCAAs to better define the indications for microsurgery.

Methods: We conducted a retrospective cohort study from 3 tertiary neurosurgical units from January 2013 to May 2020.

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Objectives: We aimed to evaluate the association between proton pump inhibitor (PPI) exposure and nosocomial infection (NI) during PICU stay.

Design: Propensity score matched analysis of a single-center retrospective cohort from January 1, 2017, to December 31, 2018.

Setting: Tertiary medical and surgical PICU in France.

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Introduction: The use of predictive low-glucose suspend (PLGS) sensor-augmented pumps has been shown to lead to a significant reduction in hypoglycemic episodes in patients with type 1 diabetes (T1D), but their effects on hyperglycemia exposure are heterogeneous. The aim of this study was to determine the settings of the Medtronic 640G system to obtain the optimal balance between occurrence of both hypoglycemia and hyperglycemia.

Methods: The hypo- and hyperglycemia area under the curve (AUC), as well as system settings [hypoglycemic threshold, mean insulin total daily dose (TDD), mean basal insulin percentage, and mean daily duration of PLGS] were collected between 2 and 12 times during 1 year in patients from four university hospital centers.

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Purpose: The objectives of the present study was to evaluate the implementation of the program in real life and the evolution of the quality of life (QoL) in breast cancer patients after 3 months of supervised PA in real life and to determine the factors associated with changes in various QoL dimensions.

Methods: This prospective cohort study was carried out in female patients with breast cancer diagnosed within a maximum of 3 yr. QoL and physical exertion intensity during the supervised physical activity (PA) sessions were assessed by the Quality of Life Questionnaire for Cancer and Borg scale, respectively.

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Background: The majority of central venous catheters (CVC) removed in the ICU are not colonized, including when a catheter-related infection (CRI) is suspected. We developed and validated a predictive score to reduce unnecessary CVC removal.

Methods: We conducted a retrospective cohort study from five multicenter randomized controlled trials with systematic catheter-tip culture of consecutive CVCs.

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Objectives: The objective of this study was to evaluate the association between ESCMID adherence and 30-day mortality in candidemia.

Methods: We performed a retrospective cohort study in two French tertiary-care hospitals. All patients with at least one positive blood culture (BC) for spp.

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Article Synopsis
  • Dolutegravir monotherapy (DTG-m) is linked to a higher risk of virological failure (VF) compared to combined antiretroviral therapy (cART) in people with HIV who were previously virologically controlled.
  • Factors increasing the risk of VF among those on DTG-m include delayed initiation of first cART after acute HIV infection, low CD4 T cell counts, and higher baseline levels of HIV RNA and DNA.
  • The study highlights the significance of a large viral reservoir in understanding the failure of DTG-m, suggesting further research is needed to explore the relationship between the size and diversity of the HIV-1 reservoir.
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Management of lumbar spinal stenosis (LSS) represents the first cause of spinal surgery for the elderly and will increase with the aging population. Although the surgery improves quality of life, the procedure involves anaesthetic and operative risks. The aim of this study was to assess whether the postoperative complication rate was higher for elderly patients and to find confounding factors.

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Objective: Postoperative pulmonary complications (PPC) remain a main issue after cardiac surgery. The objective was to report the incidence and identify risk factors of PPC after cardiac surgery.

Design: An international multicenter prospective study (42 international centers in 9 countries).

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