Publications by authors named "Anaig Flandrin"

Background: Lowe syndrome is a rare disease characterized by the association of congenital cataract, hypotonia, followed by global psychomotor delay and intellectual disability, as well as progressive renal dysfunction, and renal failure occurring at around 20 years of age.

Case Presentation: We discuss the case of a male fetus diagnosed with isolated bilateral cataract on the sonography performed at 21 + 5 weeks of gestation, confirmed by a fetal MRI at 23 weeks of gestation.After ruling out infectious etiologies, a genetic consult was conducted at 26 weeks of gestation, and an amniocentesis was realized to search for a chromosomal cause, Norrie's disease and Lowe syndrome by Sanger analysis.

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  • This clinical trial aimed to determine if daily low-dose aspirin could lower the risks of preeclampsia and fetal growth restriction in first-time pregnant women identified as high risk through early ultrasound screenings.
  • Conducted in France, the study involved over 1,100 participants who were randomly assigned to either take low-dose aspirin or a placebo from early pregnancy until the 34th week.
  • Results showed no significant difference in the rates of preeclampsia or low birth weight between the aspirin and placebo groups, leading to the conclusion that low-dose aspirin does not provide benefits for these outcomes in the targeted population.
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  • * Out of 5,450 cases of fetal anomalies, only 14 (0.3%) were diagnosed with splenic cysts, typically diagnosed around 30 weeks of gestation; most had a single cyst.
  • * By 6 months post-birth, about 36% of the cysts had completely disappeared, and although some reduced in number, nearly half still persisted without causing any symptoms.
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  • The study aimed to assess the outcomes and risks of terminating pregnancies in women with a history of caesarean sections during the second and third trimesters.
  • Conducted from January 2001 to September 2008, 67 women underwent a specific protocol involving medications like mifepristone and misoprostol, with most deliveries being vaginal and occurring within a few hours.
  • The findings showed a high vaginal delivery rate (95.5%) and a low incidence of severe complications, including a 4.8% rate of uterine rupture and only 3% experiencing significant bleeding.
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Necrotising fasciitis (NF) is the most aggressive form of soft tissue infection. We report the first case of NF of the breast following a core needle biopsy. Aggressive management including surgical debridement and vacuum therapy allowed wound healing and breast conservation.

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