Publications by authors named "Anahit M Hovhannisyan"
Amino Acids
December 2024
Article Synopsis
- A new method for creating enantiomerically enriched (S)-α-aminopropionic acid derivatives was developed using a reaction called Cu(I) catalyzed [3 + 2] cycloaddition, which combines azides with alkynes.
- The process started with a specific nickel complex and involved several key chemical components, including Schiff bases and phenyl azides.
- The absolute configuration and purity of the resulting amino acids were confirmed through advanced techniques like circular dichroism and chiral HPLC analysis, leading to the successful synthesis of seven new non-proteinogenic (S)-α-amino acids.
