Effect of phenytoin and age on gingival fibroblast enzymes.

Objective: The alteration of cytokine balance is stated to exert greater influence on gingival overgrowth compared to the direct effect of the drug on the regulation of extracellular matrix metabolism. The current study evaluated the effect of phenytoin on the regulation of collagen, lysyl oxidase and elastin in gingival fibroblasts.

Materials And Methods: Normal human gingival fibroblasts (HGFs) were obtained from 4 healthy children and 4 adults.

The plasma-rich in growth factor as a suitable matrix in regenerative endodontics: a case series.

The aim of this report is to describe the positive effect of plasma-rich in growth factor (PRGF) on pulp regeneration and apex formation in cases with necrotic pulps and open apices. After access cavity preparation and cleaning of the canal, triple antibiotic paste was inserted into the canals for the purpose of disinfection. After two weeks, apical bleeding was mechanically created by insertion of a #80 file through the apex.

Effect of Different Surface Treatments on Repair Micro-shear Bond Strength of Silica- and Zirconia-filled Composite Resins.

Background And Aims: Effect of surface treatments on repair bond strength of aged composite resins might be different due to their dissimilar fillers. The aim was to evaluate the effect of different surface treatments on repair micro-shear bond strength (µSBS) of silica- (Spectrum TPH) and zirconia-filled (Filtek Z250) composite resins.

Materials And Methods: Twenty-seven composite resin blocks were made from each type of composite resin: Z250 and Spectrum TPH.

Comparing the Efficacy of Mtwo and D-RaCe Retreatment Systems in Removing Residual Gutta-Percha and Sealer in the Root Canal.

Introduction: Retreatment is performed in teeth with unsuccessful root canal therapy or persistent apical lesion. The most important factor for achieving successful retreatment is thorough cleaning and reshaping. NiTi files and rotary instruments are widely used for the removal of obturatants.

An In Vitro Comparative Study on the Antimicrobial Effects of Bioglass 45S5 vs. Calcium Hydroxide on Enterococcus Faecalis.

Introduction: An ideal intracanal medicament should be able to eliminate any remaining intracanal microorganism. The aim of this study was to compare the antimicrobial effects of Bioglass 45S5 with calcium hydroxide on Enterococcus (E) faecalis in-vitro.

Materials And Methods: Direct exposure test (DET) was used to evaluate the antimicrobial effect of Bioglass 45S5, calcium hydroxide and normal saline (control group) on 80 paper cones contaminated with E.