Publications by authors named "Anagha Ashok Gurjar"
Article Synopsis
- Adiponectin and insulin resistance can create a cycle that makes type 2 diabetes worse.
- In male mice without a leptin receptor, they didn’t respond well to a treatment that should have helped them, while female mice did.
- A hormone called E2 helped improve the protein that helps the body use adiponectin in males, suggesting that treatments targeting hormones could help in fighting insulin resistance in diabetes.
Background: Skeletal muscle atrophy is characterized by muscle wasting with partial or complete functional loss. Skeletal muscle atrophy severely affects the quality of life and currently, there is no available therapy except for spinal muscular atrophy.
Objective: Drug repositioning is a promising strategy that reduces cost and time due to prior availability of safety and toxicity details.