Publications by authors named "Anabel Ruiz-Contreras"
Article Synopsis
- Rat thymocytes have two distinct Na+/Mg2+ exchangers, HANao and LANao, which differ in their affinities for external sodium (Na+o) and mechanisms of operation.
- The HANao exchanger is a one-to-one antiporter that is insensitive to external magnesium (Mg2+o), while LANao operates as a "ping-pong" antiporter and is significantly inhibited by Mg2+o.
- The study enhances understanding of how these exchangers are stimulated by internal magnesium levels and how they interact with sodium and magnesium ions under different conditions.
