Publications by authors named "Ana-Maria Filip"
Article Synopsis
- Type 2 diabetes mellitus (T2DM) affects around 10% of adults worldwide and can complicate the risk of conditions like gastrointestinal bleeding and cancer.
- In a study of 633 endoscopic patients, those with T2DM had lower instances of epigastric pain and heartburn, but showed significantly higher rates of anemia and lower hemoglobin and serum iron levels.
- The results suggest that while T2DM is linked to increased gastritis and certain risks, it appears to have an inverse relationship with gastroesophageal reflux symptoms, and smoking further elevates the risk of infection.
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that has been implicated in the pathogenesis of inflammatory disorders such as infection, sepsis, and autoimmune disease. MIF exists preformed in cytoplasmic pools and exhibits an intrinsic tautomerase and oxidoreductase activity. MIF levels are elevated in the serum of animals and patients with infection or different inflammatory disorders.
View Article and Find Full Text PDFIn ciliated airway epithelial cells endothelial nitric oxide synthase as well as several other membrane bound proteins are located in the apical cell pole. To date, mechanisms that serve to target and to keep these proteins in this region are unknown. Endothelial nitric oxide synthase is known to target to caveolae by interaction with caveolin-1 or caveolin-3.
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