Publications by authors named "Ana-Maria Bratovianu"
Article Synopsis
- Evolutionary selection allows naturally occurring protein assemblies to fit together optimally, which is challenging for current design methods.
- A new design approach using reinforcement learning and Monte Carlo tree search effectively samples protein shapes while considering overall architecture and function.
- The successfully designed protein structures, like nanopores and icosahedra, can enhance vaccine responses and improve angiogenesis, showcasing the efficacy of this top-down design strategy.
