Publications by authors named "Ana Werlang"

 To describe the obstetric management and perinatal outcomes in multiple pregnancies with delayed-interval delivery (DID) of the cotwin in a tertiary hospital.  This is a retrospective chart review of all cases of DID between December 2021 and 2022 at The Ottawa Hospital. Five cases of DID were identified and reviewed to obtain information on obstetric management and maternal-neonatal outcomes.

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Background Women with preeclampsia have a higher risk of cardiovascular disease. This is partly explained by the worse arterial health after preeclampsia. Central obesity (CO) is a risk factor for both preeclampsia and cardiovascular disease.

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Background: Preeclampsia (PE) is associated with increased cardiovascular risk. Recent data have shown worse left ventricular remodeling and diastolic function in women with PE and persistent hypertension (HTN). We performed a comprehensive arterial hemodynamic assessment to evaluate the contribution of persistent HTN on arterial health after PE.

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Article Synopsis
  • The study aimed to understand how Canadian obstetricians and gynecologists manage placenta accreta spectrum (PAS) disorders, focusing on their practices from diagnosis to delivery planning and the influence of national guidelines.
  • A survey conducted in 2021 received responses from 142 practitioners, revealing that almost 60% were aware of the 2019 clinical practice guidelines for PAS, with about a third altering their practices accordingly.
  • Key findings emphasized the importance of regional care, optimizing preoperative anemia, performing cesarean-hysterectomy techniques, and applying blood loss reduction strategies to improve maternal safety during PAS surgeries.
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Background Early vascular aging (EVA) is associated with higher risk of adverse cardiovascular events and can be estimated noninvasively by assessing arterial hemodynamics. Women with a history of preeclampsia have increased risk of cardiovascular disease, but underlying mechanisms are incompletely understood. We hypothesized that women with a history of preeclampsia display persistent arterial abnormalities and EVA in the postpartum period.

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 The aim of the study is to synthesize the evidence and evaluate the total cell-free deoxyribonucleic (cfDNA) associated with the prediction of preeclampsia (PE). Total cfDNA is constituted by both cell-free fetal DNA (cffDNA) originated mainly from the placenta, and maternal cfDNA derived from maternal leukocytes.  A systematic review was conducted by searching PubMed and Medline.

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