Ecotoxicological effects of a glyphosate-based herbicide on Gryllus (Gryllus) assimilis (Orthoptera: Gryllidae) ontogeny: a study on antioxidant system, oxidative stress and cholinergic system.

Brazil is an important global agricultural producer and to increase production the country has extensively used glyphosate-based herbicides (GBH), surpassing consumption and sales records. Consequently, concerns have arisen regarding the potential impact of GBH on ecosystems and non-target organisms. Thus, the effects of GBH exposure were evaluated throughout the cricket Gryllus (Gryllus) assimilis ontogeny, with five developmental stages.

Physical function as a marker to assess the effects of occupational long-term pesticide exposure.

In this cross-sectional study, we determined the relative impact of long-term occupational exposure to pesticides on physical performance and perception of tiredness. Experimental data was collected in locus from agricultural communities and included surveys to assess the duration of exposure to pesticides, social status, habitual physical activity levels, presence of common mental disorders (CMD), and self-reported tiredness. Plasmatic cholinesterase (PChE), body composition and traditional functional performance tests (Handgrip strength-HGS; Time up and go-TUG; and Sit-to-stand-STS) were obtained.

How soon do metabolic alterations and oxidative distress precede the reduction of muscle mass and strength in Wistar rats in aging process?

Here we investigate metabolic changes, the antioxidant system and the accumulation of oxidative damage in muscles with different fiber types during the aging process in Wistar rats and try to map how sooner the changes occur. To do so, 30 male Wistar rats were submitted to behavioral evaluation to determine voluntary strength in the 11, 15, and 19 month old rats, measuring the energy metabolism, antioxidant system, oxidative damage and structure in the soleus and extensor digitorum longus muscles. We detected structural and metabolic changes in both muscles, especially in the EDL of 15 month old rats and in the soleus of 19 month old rats.

Hotspots of soil pollution: Possible glyphosate and aminomethylphosphonic acid risks on terrestrial ecosystems and human health.

The study presents a literature review of glyphosate (GLY) occurrence and its breakdown product, aminomethylphosphonic acid (AMPA), in soils worldwide, but with a specific focus on South America. In addition, an ecological risk approach based on the ecotoxicological endpoints for key soil biota (e.g.

Metabolic Consequences of the Water We Drink: A Study Based on Field Evidence and Animal Model Experimentation.

The effect of the chronic consumption of water contaminated with residual concentrations of DDT's metabolites (DDD-dichlorodiphenyldichloroethane and DDE-dichlorodiphenyldichloroethylene) found in the environment were evaluated on the biometric, hematological and antioxidant system parameters of the hepatic, muscular, renal and nervous tissues of Wistar rats. The results showed that the studied concentrations (0.002 mg.

Correction: A hidden deadly venomous insect: First eco-epidemiological assessment and risk mapping of lonomism in Argentina.

[This corrects the article DOI: 10.1371/journal.pntd.

Influence of landscape ecology and physiological implications in bats from different trophic guilds.

Bats may serve as bioindicators of human impact on landscape ecology. This study aimed to evaluate the health condition of bats from different food guilds captured in two areas with different land use profiles in Brazil and to compare data on the oxidant-antioxidant balance and histopathological changes due to different anthropogenic pressures. Bats were collected from a protected area in Serra do Cipó National Park (SCNP), MG, Brazil, and an area with intense agricultural activity in the municipality of Uberaba (UB), MG, Brazil.

COVID-19 pandemic and mental health of a sample of Brazilian caregivers of people with dementia.

Unlabelled: Social distancing policies adopted in the COVID-19 pandemic generated a negative psychological impact on the general population and can affect caregivers of people with dementia more severely.

Objective: This study screened for indications of mental health problems among informal caregivers of people with dementia. Main changes in the people's routine and behavior resulting from the social isolation measures adopted due to the pandemic were also investigated.

Miniaturized QuEChERS extraction method for the detection of multi-residue pesticides in bat muscle tissue.

Habitat loss and fragmentation are among the greatest threats to biodiversity and ecosystem stability, with physiological implications on wild fauna. Bats (Microchiroptera) are small mammals with a wide variety of eating habits, and the well-being of these animals is disturbed by exposure to pesticides. This study aimed to develop a miniaturized QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) extraction method for the detection of multi-residue pesticides in bat muscle tissue using gas chromatography coupled with mass spectrometry (GC-MS).

Development of a histopathological index for skeletal muscle analysis in Rattus norvegicus (Rodentia: Muridae).

Skeletal muscle histopathological changes induced or caused by pathologies in animal models, can impair functionality, being the main focus of therapeutic studies. This study aimed to propose a histopathological index to assess, in a quantitative manner, skeletal muscle changes induced by experimental protocols for Rodentia's models. For the development, evaluation of fit and parsimony, replicability, and sensitivity index, Wistar rats from experiments with the same experimental design, but with different variation factors, were used to achieve different levels of damage.

Cyantraniliprole impairs reproductive parameters by inducing oxidative stress in adult female wistar rats.

Cyantraniliprole is a synthetic insecticide used to control pests of up to 23 different types of crops. It is able to modulate ryanodine-like calcium channels, which are widely found in the organism of insects and mammals. The objective of this research was to verify the possible reproductive effects of adult female Wistar rats exposure to cyantraniliprole.

Land use as an effective factor on the occurrence of chromosomal diseases in Brazil.

Background: The occurrence of chromosomal diseases is a worldwide health problem. The use of agrochemicals, urbanization processes, and solar radiation can be predictive factors of the elevated risk of congenital malformations. In this sense, predicting the geographical potential of the distribution of chromosomal diseases has high relevance for public health.

Comparison of gluteus medius strength between individuals with obesity and normal-weight individuals: a cross-sectional study.

Background: The hip abductor muscles, primarily the gluteus medius, play an important role in stabilizing the pelvis during gait. Gluteus medius weakness is associated with biomechanical changes and musculoskeletal disorders. Individuals with obesity can have great difficulty maintaining abductor muscular function due to being overweight and possibly experiencing a decrease in muscle mass.

Biochemical predictors for metabolic syndrome in preterm infants according to weight ratio.

Objective: Prematurity and low birth weight predispose preterm infants to cardiovascular disease in later life. Is the metabolic profile of these children impacted by the relation between birth weight and gestational age (GA)? This study aimed to evaluate whether the relationship between birth weight and GA of preterm infants has a positive correlation with the metabolic profile from birth to the sixth month of corrected age.

Methods: This is a longitudinal, prospective study with a cohort of 70 preterm and 54 term infants, who were enrolled in the study and shared into two groups: Appropriate for GA (AGA) and Small for GA (SGA), both classified at birth by Fenton and Kim curves.

Pregnancy and lactation after Roux-en-Y gastric bypass worsen nonalcoholic fatty liver disease in obese rats and lead to differential programming of hepatic lipogenesis in offspring.

Maternal obesity increases the risk of nonalcoholic fatty liver disease (NAFLD) in offspring. The Roux-en-Y gastric bypass (RYBG) is effective for achieving weight loss and ameliorates NAFLD. To determine whether these benefits are maintained after pregnancy and/or lactation, and whether they modulate hepatic morphofunction in the next generation, we evaluated hepatic lipid metabolism in Western diet (WD)-obese female rats that underwent RYGB and in their F1 offspring at adulthood.

Alterations in neuromuscular junctions and oxidative stress of the soleus muscle of obese Wistar rats caused by vibratory platform training.

Objectives: evaluate the effects that whole-body vibration (WBV) causes on the neuromuscular junctions and oxidative stress of the soleus muscle of obese rats.

Methods: 32 male rats were used, 16 of which were obesity induced by monosodium glutamate, randomized into four groups: control (GC), control with WBV (GCP), obese (GO) and obese with WBV (GOP). At the 70 days old, the training on WBV was started, performed 3 times a week, during 8 consecutive weeks.

Whole-body vibration promotes lipid mobilization in hypothalamic obesity rat.

Objectives: This study aimed to analyze the effect of whole-body vibration (WBV) on metabolic parameters using the monosodium l-glutamate (MSG) model of obesity.

Method: MSG-obese rats that were exposed to WBV on a vibrating platform with 60 Hz frequency, 2 mm amplitude, three times/week, 10 min/day, during eight weeks (from postnatal day (PN) 80 to PN136). Blood glucose, creatine kinases (CK and CK-MB) and lipid profile through plasma and liver levels of lipids and lipoproteins were evaluated.

Extended light period in the maternal circadian cycle impairs the reproductive system of the rat male offspring.

Alterations in the circadian cycle are known to cause physiological disorders in the hypothalamic-pituitary-adrenal and the hypothalamic-pituitary-gonadal axes in adult individuals. Therefore, the present study aimed to evaluate whether exposure of pregnant rats to constant light can alter the reproductive system development of male offspring. The dams were divided into two groups: a light-dark group (LD), in which pregnant rats were exposed to an LD photoperiod (12 h/12 h) and a light-light (LL) group, in which pregnant rats were exposed to a photoperiod of constant light during the gestation period.

Exposure to pesticides in bats.

Bats provide a variety of ecological services that are essential to the integrity of ecosystems. Indiscriminate use of pesticides has been a threat to biodiversity, and the exposure of bats to these xenobiotics is a threat to their populations. This study presents a review of articles regarding the exposure of bats to pesticides published in the period from January 1951 to July 2020, addressing the temporal and geographical distribution of research, the studied species, and the most studied classes of pesticides.

Short-term effects of whole-body vibration on the soleus of ooforectomized rats: Histomorphometric analysis and oxidative stress in an animal model.

Purpose: The aim of this study was to analyze the effects of mechanical vibration on the histomorphometry and oxidative stress of oophorectomized rats.

Method: Seventy-two Wistar rats were randomized to Pseudoophorectomy (P) and Oophorectomy (O) and subdivided into untreated animals and euthanized after four (P4 and O4) and eight (P8 and O8) weeks and animals treated during four (PT4 and OT4) and eight (PT8 and OT8) weeks. The treatment consisted of use of whole-body vibration for 10 min, three times a week.

Seasonal records of benthic macroinvertebrates in a stream on the eastern edge of the Iguaçu National Park, Brazil.

Iguaçu National Park (INP) is known worldwide due to Iguaçu Waterfalls, being considered a World Natural Heritage by UNESCO. The INP is one of the last large forested extensions of inland Brazil that provides protection to the Atlantic Forest, one of the world's biodiversity hotspots. However, its Natural Heritage status has been threatened by the construction and operation of the Baixo Iguaçu dam, agricultural and urban impacts on its boundaries and the increasing interest of the Brazilian government in re-opening of the "Colono road", an old illegal road that crossed the interior of the park.

Morphological effects of whole-body vibration on remobilization of the tibialis anterior muscle of Wistar rats.

Therapeutic immobilization is a common treatment for the locomotor system; however, it causes loss of muscle due to disuse, leading to protein degradation and generating atrophy of muscle cells, ultimately changing functionality. In this sense, it is important for remobilization to be initiated early and performed with appropriate therapeutic strategies that enable tissue and functional recovery. One method of remobilization is physical exercise, among which whole body vibration (WBV) has been highlighted and mainly applied in people with reduced mobility.