Intraocular pressure rise during 25-gauge vitrectomy trocar placement.

Purpose: Small-gauge vitrectomy has been used to treat various vitreous and macular pathologies. Trocar/cannula insertion may raise intraocular pressure (IOP) to the point it might become detrimental to the eye, especially in the setting of open-globe trauma and eyes with severe vascular compromise. We propose to determine the magnitude of this IOP rise and its possible implications.

Human lymphocyte antigen DR7 protects against proliferative retinopathy with type II diabetes mellitus.

Background: This study was undertaken in order to analyze the genetic incidence of human lymphocyte antigen diabetic retinopathy (HLA-DR) and its influence in proliferative diabetic retinopathy (PDR).

Methods: We designed a case-control study in which 127 mestizo Mexican patients with DM II and diabetic retinopathy were studied. DNA was extracted and HLA-DR regions were amplified using PCR.