Publications by Ana S Coxixo

Publications by authors named "Ana S Coxixo"

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Human Aquaporin-5 Facilitates Hydrogen Peroxide Permeation Affecting Adaption to Oxidative Stress and Cancer Cell Migration.

Claudia Rodrigues Catarina Pimpão Andreia F Mósca Ana S Coxixo Duarte Lopes

Cancers (Basel)

July 2019

Reactive oxygen species (ROS), including HO, contribute to oxidative stress and may cause cancer initiation and progression. However, at low concentrations, HO can regulate signaling pathways modulating cell growth, differentiation, and migration. A few mammalian aquaporins (AQPs) facilitate HO diffusion across membranes and participate in tumorigenesis.

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Ana S Coxixo's recent research highlights the role of Human Aquaporin-5 in the permeation of hydrogen peroxide, linking it to adaptive responses to oxidative stress and the migration of cancer cells.
The study emphasizes the dual nature of reactive oxygen species, particularly hydrogen peroxide, suggesting that while high concentrations can lead to cancer, low levels may play a regulatory role in crucial signaling pathways.
Published in the journal 'Cancers (Basel)', this work contributes to understanding how certain aquaporins facilitate hydrogen peroxide diffusion, indicating their potential involvement in tumor development and progression.

Publications by authors named "Ana S Coxixo"

Human Aquaporin-5 Facilitates Hydrogen Peroxide Permeation Affecting Adaption to Oxidative Stress and Cancer Cell Migration.

Synopsis of recent research by authors named "Ana S Coxixo"