Publications by authors named "Ana Raquel Santiago"
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Synopsis of recent research by authors named "Ana Raquel Santiago"
- Ana Raquel Santiago's research primarily focuses on the neuroprotective roles of Müller glial cells and microglia in retinal diseases, particularly glaucoma and diabetic retinopathy, linking neuroinflammation to retinal ganglion cell (RGC) degeneration.
- Her recent studies have demonstrated that Müller glial cells in the peripheral retina are particularly sensitive to elevated pressure, contributing to RGC death, while also exploring the impact of microglial activation on neuroinflammatory processes in retinal injuries.
- Santiago has also investigated therapeutic approaches, including the use of adenosine A receptor agonists and antagonists to mitigate inflammation and protect RGCs from ischemic and pressure-induced damage, indicating potential pathways for clinical intervention in retinal degenerative diseases.