Publications by authors named "Ana Rakonjac"
Genetic counselors (GCs) face unique challenges in the acute care setting. Acute care environments-such as neonatal and pediatric intensive care units-are characterized by urgency, complexity, and rapid decision making. These settings require GCs to navigate a delicate balance between addressing the immediate clinical needs of patients and providing comprehensive genetic information to families, while demanding adaptation of existing skills for practice.
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- - The Acute Care Genomics program in Australia offered whole-genome sequencing to 290 families of critically ill children over 2 years, achieving an average result time of 2.9 days and a diagnostic yield of 47%.
- - Further analysis and advanced sequencing methods led to 19 additional diagnoses, increasing the overall diagnostic yield to 54%, with various genetic issues identified.
- - Among the diagnosed patients, 77% experienced changes in critical care management, significantly influencing treatment options, surgeries, and palliative care in 60% of cases, highlighting the effectiveness of integrating advanced genomic approaches into regular diagnostic practices.
Article Synopsis
- - Maternal vitamin D deficiency can negatively affect fetal development and may lead to neurodevelopmental issues in offspring, potentially due to increased exposure to glucocorticoids during pregnancy.
- - The research aimed to verify if excess glucocorticoids during prenatal stages in their rat model of vitamin D deficiency caused behavioral changes in adults.
- - Results showed that vitamin D deficiency reduced a specific enzyme related to glucocorticoid inactivation in the placenta, but did not impact overall maternal glucocorticoid levels or other factors, revealing differences from findings in vitamin D deficient mice.
We describe the construction of a motorized optical rotation mount with a 40 mm clear aperture. The device is used to remotely control the power of large diameter laser beams for a magneto-optical trap. A piezo-electric ultrasonic motor on a printed circuit board provides rotation with a precision better than 0.
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