Publications by authors named "Ana Posada"

Article Synopsis
  • The intersection of ageing and spinal cord injury (SCI) presents two main scenarios: an increase in average age of SCI onset, and longer life after injury, both leading to complex healthcare and rehabilitation needs.
  • A review of Clinical Practice Guidelines (CPGs) found that only 30% of them addressed ageing-related recommendations for rehabilitation, mostly from recent US or European sources, and lacking comprehensive sections on ageing issues.
  • Although there were 40 ageing-related recommendations, they were often based on low-quality evidence and did not adequately incorporate stakeholder values, with notable gaps in the overall quality and completeness of guidance on associated health conditions.
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Background: The world population is ageing rapidly. Rehabilitation is one of the most effective health strategies for improving the health and functioning of older persons. An understanding of the current provision of rehabilitation services in primary care (PC) is needed to optimise access to rehabilitation for an ageing population.

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Background And Objective: In some cases, for the evaluation of the health status of patients it is not possible to obtain data directly from the patient. The objective of this study was to determine if the instruments that cannot be applied to the patient can be completed by a proxy.

Methods: A systematic review of the literature was carried out and 20 studies were included.

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Background: To increase people's access to rehabilitation services, particularly in the context of the COVID-19 pandemic, we need to explore how the delivery of these services can be adapted. This includes the use of home-based rehabilitation and telerehabilitation. Home-based rehabilitation services may become frequently used options in the recovery process of patients, not only as a solution to accessibility barriers, but as a complement to the usual in-person inpatient rehabilitation provision.

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Objective: To synthesize information on the psychometric properties of scales used to assess vision-related quality of life in people with low vision.

Methods: A systematic review was conducted. The Cochrane Library, Embase, PubMed, Bireme and Epistemonikos databases were consulted in July 2020.

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Background: Gender disparities exist worldwide related to female representation in digital health initiatives especially in low and middle income countries (LMICs). Upstream approaches and policy implementation has been effective in some countries to reduce the gender gap in the areas of political and sector leadership. At an international digital health conference in Bolivia, all-male expert panels presented their research and innovations to audiences from the Bolivian national and regional health departments and private and non-governmental organization heath leaders.

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Triple-negative breast cancer (TNBC) is a heterogeneous and complex disease characterized by the absence of immunohistochemical expression of estrogen receptor, progesterone receptor and HER2. These breast tumors present an aggressive biology and offer few opportunities to be treated with targeted therapy resulting in bad disease outcomes. The epidemiology of TNBC is intriguing where the understanding of its biology has progressed quickly.

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Breast cancer (BC) is a highly prevalent malignancy in Latin American women, most cases being diagnosed at locally advanced or metastatic stages when options for cancer care are limited. Despite its label as a public health problem in the region, Latin American BC patients face several barriers in accessing standard of care treatment when compared with patients from developed countries. In this review, we analyse the landscape of the four main identified barriers in the region: i) high burden of locally advanced/advanced BC; ii) inadequate access to medical resources; iii) deficient access to specialised cancer care and iv) insufficient BC research in Latin America.

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In Staphylococcus aureus, the low-molecular-weight thiol called bacillithiol (BSH), together with cognate S-transferases, is believed to be the counterpart to the glutathione system of other organisms. To explore the physiological role of BSH in S. aureus, we constructed mutants with the deletion of bshA (sa1291), which encodes the glycosyltransferase that catalyzes the first step of BSH biosynthesis, and fosB (sa2124), which encodes a BSH-S-transferase that confers fosfomycin resistance, in several S.

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