Publications by authors named "Ana Pl Assad"
Article Synopsis
- The study aimed to identify factors associated with mortality in pediatric patients with childhood-onset systemic lupus erythematosus (cSLE) by analyzing clinical data and determining frequent causes of death.
- Researchers reviewed medical records of 1,528 cSLE patients from 27 centers in Brazil and found that 63 patients died, primarily due to sepsis and opportunistic infections, with significant mortality risks linked to neuropsychiatric lupus and chronic kidney disease.
- Although the overall survival rates for cSLE patients after diagnosis were high (97% at 5 years), the findings highlight the need for better management of high-risk conditions in these patients.
Objective: To evaluate if the 2019-European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) criteria at diagnosis of childhood-onset systemic lupus erythematosus (cSLE) are associated with higher rates of early damage scored by Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index (SDI).
Methods: This retrospective multicenter study included 670 cSLE patients with ≤5 years of disease duration. All patients fulfilled both 2019-EULAR/ACR and 1997-ACR classification criteria.