"Acute responses to barefoot running are related to changes in kinematics, mechanical load, and inflammatory profile".

This study investigated the acute effects of barefoot (BF) running on biomechanical parameters and cytokine concentrations. Seventy-one habitually shod runners had biomechanical parameters evaluated during running shod (SH) and BF, while a sub-group of 19 runners had their inflammatory profile analyzed before and after a running session, using their habitual shoes or barefoot. Running BF changed spatiotemporal and joint kinematics, including the stride frequency (increased) and length (decreased), and foot strike pattern (more plantarflexed ankle at initial contact).

Aging effects of haptic input on postural control under a dual-task paradigm.

Postural control relies on three principal sensory systems: vision, vestibular and proprioceptive; that are affected by aging. When performing a cognitive task concomitantly with a motor task, those sensory impairments lead to even greater deleterious effects on balance. We aimed to study the effects of a sensory aid (a light touch) on a dual task paradigm and sought to understand the different responses on balance due to aging.

Immediate effects of a real moderate interval-running training session on inflammatory profile.

The study investigated the immediate effect of a moderate interval-running training session on circulating inflammatory cytokines concentration at real conditions of training. Nine recreational runners (5 women and 4 men; 68,33 ± 10,20 kg; 1,65 ± 0,07 m; 28,67 ± 4,24 years) had blood samples collected from antecubital vein before and immediately after a moderate interval-running training session without fasting. Cytokine levels were obtained from blood samples through Multiplex Analysis of Sample Protein Content, performed by Magpix® instrument.

Creatine supplementation can improve impact control in high-intensity interval training.

Objectives: This study aimed to investigate the effects of creatine (Cr) supplementation on biomechanical parameters related to shock attenuation during a session of high-intensity interval training (HIIT).

Methods: A single-blinded, placebo-controlled, crossover design was adopted to test eight male elite soccer players during HIIT sessions under two conditions: after placebo supplementation and after Cr supplementation. HIIT test sessions consisted of an intermittent test (five bouts of running) with a constant load applied until exhaustion was reached.

Perception of impact is affected by stimulus intensity.

Perception of external loads may be a central topic to understand adjustments to the mechanical demands during movement. Nevertheless, the association between the perceived and the real load received is still controversial. This study aimed to correlate vertical ground reaction force (vGRF) to the perception of impact in different regimens of stimulus application.

Does "transition shoe" promote an intermediate biomechanical condition compared to running in conventional shoe and in reduced protection condition?

This study evaluated if running in a "transition shoe" commercially available results in intermediate mechanical load upon lower extremities compared to conventional shoe and minimalist shoe/barefoot. Kinematic and kinetic parameters while running in different shoe conditions were compared. Fourteen runners (12 men, 2 women; age=28.

Genotoxic effects of the antileishmanial drug Glucantime.

Leishmaniasis is caused by species of the protozoan parasite Leishmania. It is the third most important vector-borne disease and is widely distributed throughout the world. The World Health Organization recommends pentavalent antimonials as drugs of first choice in its treatment.