Diagnosis and follow-up of keratoacanthoma-like lesions: clinical-histologic study of 43 cases.

Background: Keratoacanthoma (KA) is easily confused with squamous cell carcinoma (SCC) on a clinical or a histopathologic basis. However, KA undergoes spontaneous regression, whereas SCC does not.

Objective: Our objective was to study the histopathologic features associated with clinical regression in KA-like lesions to support the therapeutic option.