Publications by authors named "Ana Paula Magalhaes-Nunes"
Article Synopsis
- The study explored how 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus (DRN) influence salt intake in rats, particularly during sodium depletion.
- Acute administration of 8-OH-DPAT, a 5-HT(1A) agonist, led to increased salt intake, indicating its role in promoting salt preference.
- Chronic treatment with 8-OH-DPAT, however, reduced salt intake over time in sodium-depleted rats, suggesting these autoreceptors play a significant role in regulating both immediate and long-term responses to sodium levels.
We investigated the effects of chronic administration of sertraline (SERT; approximately 20 mg kg(-1) day(-1) in drinking water), a selective serotonin reuptake inhibitor, on water and sodium intake and on plasma levels of oxytocin (OT) and vasopressin (AVP) in basal and stimulated conditions. Basal water intake was reduced in SERT-treated rats. After 24 h of water deprivation, rats treated with SERT for 21 days ingested less water than the control rats (9.
View Article and Find Full Text PDF