"Acute responses to barefoot running are related to changes in kinematics, mechanical load, and inflammatory profile".

This study investigated the acute effects of barefoot (BF) running on biomechanical parameters and cytokine concentrations. Seventy-one habitually shod runners had biomechanical parameters evaluated during running shod (SH) and BF, while a sub-group of 19 runners had their inflammatory profile analyzed before and after a running session, using their habitual shoes or barefoot. Running BF changed spatiotemporal and joint kinematics, including the stride frequency (increased) and length (decreased), and foot strike pattern (more plantarflexed ankle at initial contact).

Creatine supplementation can improve impact control in high-intensity interval training.

Objectives: This study aimed to investigate the effects of creatine (Cr) supplementation on biomechanical parameters related to shock attenuation during a session of high-intensity interval training (HIIT).

Methods: A single-blinded, placebo-controlled, crossover design was adopted to test eight male elite soccer players during HIIT sessions under two conditions: after placebo supplementation and after Cr supplementation. HIIT test sessions consisted of an intermittent test (five bouts of running) with a constant load applied until exhaustion was reached.

Atypical haematological presentation in a case of polycythaemia vera with a new variant mutation detected in exon 12: c.1605G>T (p.Met535Ile).

One of the major genetic insights into the pathogenesis of polycythaemia vera included the identification of the somatic point gain-of-function mutations in Janus kinase 2 gene-first on exon 14, present in 95%-97% of the cases, and later on exon 12. In the literature, we can find some reported studies where different exon 12 mutations are identified. Unlike patients with mutation in exon 14, the mutation at exon 12 is not usually associated with an increase in the three haematopoietic series (erythrocytosis, leucocytosis and thrombocytosis).

Correction: 16 Weeks of Progressive Barefoot Running Training Changes Impact Force and Muscle Activation in Habitual Shod Runners.

[This corrects the article DOI: 10.1371/journal.pone.

16 Weeks of Progressive Barefoot Running Training Changes Impact Force and Muscle Activation in Habitual Shod Runners.

Short-term effects of barefoot and simulated barefoot running have been widely discussed in recent years. Consequences of adopting barefoot running for a long period, including as a training approach, still remain unknown. The present study evaluated the influence of 16 weeks of progressive barefoot running training on impact force and muscle activation in habitual shod runners.

Does "transition shoe" promote an intermediate biomechanical condition compared to running in conventional shoe and in reduced protection condition?

This study evaluated if running in a "transition shoe" commercially available results in intermediate mechanical load upon lower extremities compared to conventional shoe and minimalist shoe/barefoot. Kinematic and kinetic parameters while running in different shoe conditions were compared. Fourteen runners (12 men, 2 women; age=28.

Effects of replica running shoes upon external forces and muscle activity during running.

Twelve participants ran (9 km · h(-1)) to test two types of running shoes: replica and original shoes. Ground reaction force, plantar pressure and electromyographic activity were recorded. The shoes were tested randomly and on different days.