Evaluation of methods in detecting vancomycin MIC among MRSA isolates and the changes in accuracy related to different MIC values.

Introduction: Methicillin-Resistant Staphylococcus aureus (MRSA) presenting reduced susceptibility to vancomycin has been associated to therapeutic failure. Some methods used by clinical laboratories may not be sufficiently accurate to detect this phenotype, compromising results and the outcome of the patient.

Objectives: To evaluate the performance of methods in the detection of vancomycin MIC values among clinical isolates of MRSA.

Phenotypic, molecular and antimicrobial susceptibility assessment in isolates from chronic ulcers of cured leprosy patients: a case study in Southern Brazil.

Background: One of the most stigmatizing physical sequelae of leprosy in cured patients is the development of chronic lower extremity ulcers. The bacterial diversity present in ulcers is considered one of the factors that can delay the healing process, as well as serve as a focus for severe secondary infections.

Objective: To identify the microbiota and antimicrobial resistance profile of bacteria isolated from skin ulcers in patients cured of leprosy.

Community-acquired methicillin-resistant Staphylococcus aureus carrying SCCmec type IV in southern Brazil.

Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen commonly associated with nosocomial infections. However, it has also been associated with community-acquired skin and soft tissue infections (CA-MRSA). There are few data on the identification and prevalence of CA-MRSA infections in Brazil.

[Methicillin-resistant Staphylococcus aureus: emerging community dissemination].

Staphylococcus aureus is responsible for a broad variety of infectious diseases. The main concern is about methicillin-resistant isolates (MRSA), which are usually limited to hospitals. In recent years, community associated or acquired MRSA infections (CA-MRSA) have been frequently reported and emerged in the world.

[Sepsis due to community-acquired methicillin-resistant Staphylococcus aureus in southern Brazil].

Methicillin-resistant Staphylococcus aureus was initially described as a typical microorganism acquired in nosocomial infections. However, over recent years, community-acquired methicillin-resistant Staphylococcus aureus has been a cause of skin and soft-tissue infections. Serious infections such as pneumonia and sepsis can also occur.