Publications by authors named "Ana Paula Arias"

At present, different reports have shown that children reach similar SARS-CoV-2 viral load (VL) levels compared to adults; however, the impact of VL on children remains ambiguous when asymptomatic versus symptomatic cases are compared. Thus, the aim of this study was to assess VL at the time of diagnosis in asymptomatic and symptomatic SARS-CoV-2 infected children. VL analysis was retrospectively carried out from nasopharyngeal swabs on 82 SARS-CoV-2 infected children, from March to October 2020.

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Article Synopsis
  • The study aims to analyze the clinical characteristics, resource utilization, and outcomes of children with COVID-19 at Garrahan Pediatric Hospital in Buenos Aires during the first 20 weeks after the first case was detected.
  • A total of 280 pediatric patients were examined, revealing the majority had mild cases, with a median age of 83 months and a significant number requiring hospitalization.
  • Key observations include that many patients had underlying health conditions, and there was a higher demand for intensive care resources in the early weeks of the pandemic, although only 0.7% of patients died, primarily due to severe comorbidities.
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Objective: To evaluate the differential characteristics of SARS-COV-2 associated inflammatory multisystem syndrome (MIS-C) in children.

Methods: A retrospective cohort study was conducted.  The definition of MIS- C was based on WHO criteria.

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An 8-month-old child was admitted to a paediatric intensive care unit in Guinea-Bissau with severe blistering dermatosis. He was treated with broad spectrum antibiotics and dressings, without improvement. After 2 weeks, linear IgA bullous dermatosis was suspected.

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Guillain-Barré syndrome is defined as an acute polyradiculoneuropathy, with sudden onset and its origin being mostly autoimmune. It is characterized by flaccid paralysis, symmetrical and ascending, together with areflexia, with or without sensory disturbances. It is the primary cause of acute flaccid paralysis in previously healthy children.

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Primary pyomyositis is an acute bacterial infection of skeletal muscle leading to single or multiple abscess formation. The etiologic agent most frequently identified is Staphylococcus aureus, principal emerging pathogen of invasive musculoskeletal infections in otherwise healthy children. It is important to maintain a high level of suspicion, since early diagnosis and effective empirical treatment may prevent progression to a more severe disease.

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