Publications by authors named "Ana Morales Callaghan"
Article Synopsis
- The study examines the use of guselkumab for treating psoriasis in patients with a history of cancer, addressing the limited guidance available for such cases.
- A total of 20 patients were followed over 52 weeks, with high effectiveness rates seen (87.5% achieving a low psoriasis severity score) and a 100% survival rate, including those with active cancers.
- The findings suggest guselkumab is both effective and safe in this population, though the study is limited by its small sample size and retrospective design.*
Biologic treatments are increasingly being used in the management of moderate to severe plaque psoriasis (PSO). Risankizumab (RZB) is a humanized monoclonal antibody that specifically blocks the p19 subunit of interleukin 23, which in turn regulates the activation, differentiation, and survival of Th17. RZB has proved their efficacy and their safety compared to anti-TNF.
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- * A survey of 34 participants demonstrated notable improvements in the quality of life scores, with significant reductions in symptoms and overall usability ratings showing the system's reliability.
- * Patients found the virtual assistant helpful, leading to 52 medical consultations, and the study highlighted a slight increase in treatment adherence, suggesting the system provides security and better access to healthcare.
After the beginning of the SARS-CoV-2 pandemic, our dermatology department created a multidisciplinary unit to manage patients with cutaneous manifestations associated with COVID-19. With the objective of identifying skin lesions in patients with suspected COVID-19 and evaluating possible associations with systemic involvement, other infectious agents and coagulation disorders, we carried out a prospective observational study that included all patients that attended our COVID-19 dermatology clinic with a multidisciplinary protocol. A total of 63 patients (mean 34.
View Article and Find Full Text PDFWe report the case of a patient with a black and turquoise tattoo who developed sarcoid granulomas on the areas of black pigment. Patch tests showed a positive reaction to nickel, cobalt, and cadmium; spectrophotometric analysis of the black pigment revealed the presence of nickel and cobalt among other metals. Although the pathogenesis of sarcoid granulomas is unknown, it seems that a delayed type hypersensitivity reaction is one of the mechanisms involved.
View Article and Find Full Text PDFWe describe a new case of annular atrophic lichen planus. Annular atrophic lichen planus is a rare variant of lichen planus that is clinically characterized by violaceous plaques of annular morphology with central atrophy and histopathologic findings of annular and atrophic lichen planus, respectively. There have been 4 cases of this entity reported previously.
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