Publications by authors named "Ana Monica Turcios-Esquivel"
Immunomodulatory Activity of Diterpenes over Innate Immunity and Cytokine Production in a Human Alveolar Epithelial Cell Line Infected with .
Alejandro David Hernández-Herrera Julieta Luna-Herrera Marisela Del Rocío González-Martínez Adria I Prieto-Hinojosa Ana Monica Turcios-Esquivel
Curr Mol Pharmacol
May 2023
Article Synopsis
- - The study focuses on three diterpenes from Salvia ballotiflora, evaluating their immunomodulatory effects on innate immunity and cytokine production in human alveolar cells infected with Mycobacterium tuberculosis.
- - Findings indicate that anastomosine and 7,20-dihydroanastomosine significantly boost reactive nitrogen species (RNS) production after 36 hours and reactive oxygen species (ROS) after 12 hours post-treatment, showcasing their potential role in enhancing innate immunity.
- - The diterpenes exhibited an anti-inflammatory effect by modulating TGF-β levels; however, they did not significantly affect TNF-α release, suggesting a selective immune response to the tuberculosis infection.