Publications by authors named "Ana Menasalvas"

Article Synopsis
  • In 2023, Europe raised concerns about rising severe neonatal infections due to a new lineage of echovirus 11 (E11), prompting an analysis of E11 cases in Spain from 2019 to 2023.
  • Out of 1,288 samples, 103 were found to be E11-positive, but the detection rates and severity of infections among neonates did not significantly change after the new lineage appeared in June 2022.
  • The findings suggest that the new lineage 1 is not responsible for increased neonatal infections, but the discovery of novel E11 recombinants linked to severe cases highlights the need for better monitoring and surveillance.
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We aimed to identify the spectrum of disease in children with COVID-19, and the risk factors for admission in paediatric intensive care units (PICUs). We conducted a multicentre, prospective study of children with SARS-CoV-2 infection in 76 Spanish hospitals. We included children with COVID-19 or multi-inflammatory syndrome (MIS-C) younger than 18 years old, attended during the first year of the pandemic.

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Enteroviruses (EVs) and human parechoviruses (HPeVs) are a major cause of central nervous system (CNS) infection in young infants. They have been implicated in neurodevelopmental delay, however limited data are available. The aim of this study is to describe the clinical outcome of young infants and to assess and compare the medium-term neurodevelopment following CNS infections caused by EV and HPeV.

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Background: There are not enough nationwide studies on perinatal HIV transmission in connection with a combination of antiretroviral treatments in Spain. Our objectives were to study sociodemographic changes and trends in the rates of HIV diagnoses and perinatal transmission in Spain from 1997 to 2015.

Methods: A retrospective study using data from Spanish Paediatric HIV Network (CoRISpe) and Spanish Minimum Basic Data Set (MDBS) was performed.

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Article Synopsis
  • - Human parechovirus (HPeV) is a recently identified virus linked to serious conditions like fever of unknown origin and meningitis in young infants; this study aimed to explore its epidemiology and clinical features.
  • - Over three years, a study in 12 hospitals in Spain found that 5.52% of 850 specimens tested positive for HPeV, predominantly HPeV-3, with most cases occurring in neonates, highlighting symptoms such as fever, irritability, and gastrointestinal issues.
  • - The study concluded that HPeV infections primarily occur in the spring and summer months, with a significant number of infants experiencing severe symptoms; it suggested that enhanced molecular diagnostic methods could improve patient care.
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