Publications by authors named "Ana Maria do Amaral Cerqueira"
Thromb Haemost
January 2011
Article Synopsis
- The development of alloantibodies against factor VIII is a major complication in treating congenital hemophilia A, affecting patient outcomes.
- During a study from 1993 to 2006, data was collected on patients' inhibitor tests and factor infusions, showing that 12% tested positive for inhibitors at least twice.
- Most patients with low inhibitor levels (< 5 BU/ml) achieved a sustained negative status, suggesting that immune tolerance induction may not be necessary for those with lower inhibitor titres.
- Further research is needed to identify factors influencing sustained negative status in regions lacking ITI treatment options.
