Publications by authors named "Ana Maria Vegas Alvarez"
Unlabelled: Tumor-necrosis-factor-α inhibitors (anti-TNF-α) are associated with an increased risk of tuberculosis (TB) disease, primarily due to reactivation of latent TB infection (LTBI). We assessed the performance of parallel LTBI screening with tuberculin skin test (TST) and QuantiFERON-TB Gold In-Tube assays (QFT-GIT) before anti-TNF-α treatment in children with immune-mediated inflammatory disorders in a low TB-burden setting. We conducted a multicenter cohort study involving 17 pediatric tertiary centers in Spain.
View Article and Find Full Text PDFDiagnostic action against hypertransaminasemia in paediatrics: Consensus document of Sociedad Española de GastroenterologÃa, HepatologÃa y Nutrición Pediátrica (SEGHNP), Asociación Española de PediatrÃa de Atención Primaria (AEPap) and Sociedad Española de PediatrÃa de Atención Primaria (SEPEAP).
An Pediatr (Engl Ed)
May 2022
Article Synopsis
- Hypertransaminasemia is a common issue in children that may indicate serious medical conditions that can be treated.
- The document aims to provide a consensus on how to manage hypertransaminasemia from detection to diagnosis by reviewing existing evidence.
- A working group from key pediatric organizations developed 21 practical recommendations to aid medical professionals in both hospitals and primary care settings.
The management of Helicobacter pylori infection in children is a consistent problem in clinical practice. Over the years, many questions have been raised regarding symptoms associated with the infection, the diagnostic methods and type of treatment. What is most controversial is determining the criteria that enable us to initiate and carry out the study in children.
View Article and Find Full Text PDFThe management of Helicobacter pylori infection in children is a consistent problem in clinical practice. Over the years, many questions have been raised regarding symptoms associated with the infection, the diagnostic methods and type of treatment. What is most controversial is determining the criteria that enable us to initiate and carry out the study in children.
View Article and Find Full Text PDFArticle Synopsis
- Exclusive enteral nutrition (EEN) is more effective than corticosteroids for achieving mucosal healing in children with Crohn's disease, without the negative side effects of steroids.
- A study covering 222 newly diagnosed pediatric patients found that 83% achieved clinical remission after an average of 8 weeks of EEN, with significant reductions in faecal calprotectin levels.
- Factors predicting a better response to EEN include specific scores on the Crohn's disease activity index, lower calprotectin levels, elevated CRP, and ileal involvement, suggesting EEN should be first-line treatment for pediatric Crohn's disease.