Publications by authors named "Ana Maria Soldo"
Article Synopsis
- Obesity leads to fat buildup and oxidative stress, often increasing lipid peroxidation and producing harmful substances like 4-HNE.
- This study assessed how weight loss from bariatric surgery affects lipid peroxidation and lipid profiles in obese individuals.
- Results showed significant reductions in lipid peroxidation markers and a notable decrease in BMI after six months post-surgery; however, more research is required to fully understand the connections between obesity, oxidative stress, and metabolic changes resulting from the surgery.
Obesity and chronic oxidative stress, often being associated with each other in a vicious circle, are important factors of chronic diseases. Although it was usually considered to accompany aging and wealth, global trends show the increase in obesity among children even in Third World countries. Being manifested by an imbalance between energy consumption and food intake, obesity is characterized by an excessive or abnormal fat accumulation, impaired redox homeostasis and metabolic changes often associated with the self-catalyzed lipid peroxidation generating 4-hydroxynonenal, pluripotent bioactive peroxidation product of polyunsaturated fatty acids.
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