Publications by authors named "Ana Maria Lopes de Passos"
Eur J Histochem
October 2019
Article Synopsis
- STAT3 is a transcription factor activated by IL-6 and IL-10, which have opposing effects, and SOCS3 acts as a negative regulator of STAT3, crucial for controlling inflammation.
- In hyperglycemic conditions, the study found that both STAT3 and SOCS3 showed increased expression in the placenta's labyrinth and junctional zones compared to control.
- The raised levels of IL-10 in hyperglycemic placentas correlated positively with the increased expression of STAT3 and SOCS3, indicating a disrupted balance of cytokines in these conditions.
