Publications by authors named "Ana Maria Lacerda Morgado Fernandes de Carvalho de Aboim Horta"
Glomerular filtration rate change during chronic hepatitis C treatment with Sofosbuvir/Ledipasvir in HCV/HIV Coinfected patients treated with Tenofovir and a boosted protease inhibitor: an observational prospective study.
Cristina Aurora São Pedro Soeiro Celina Andreia Melo Gonçalves Marta Sofia Correia Marques Maria Josefina Vazquez Méndez Ana Paula Ribeiro Almeida Tavares Ana Maria Lacerda Morgado Fernandes de Carvalho de Aboim Horta
BMC Infect Dis
August 2018
Introduction: Concomitant use of ledipasvir and boosted protease inhibitors (PIs) may increase the risk of tenofovir (TDF) nephrotoxicity, since both these drugs increase TDF levels. Our aim was to evaluate glomerular filtration rate (eGFR) evolution during HCV treatment with sofosbuvir/ledipasvir (SOF/LDV) in HCV/HIV coinfected patients, according to their antiretroviral treatment (ARV).
Methods: Observational prospective study of HCV/HIV coinfected patients treated with SOF/LDV.