The urine culture remains essential for diagnosing urinary tract infections (UTIs), but many tests yield negative results, suggesting a need for better screening methods to reduce workload and hasten negative result reporting.
The study tested the UF-1000i flow cytometer for screening urine samples, comparing results between two groups based on bacterial growth levels, showing high sensitivity and reasonable specificity in identifying negative cases for both groups.
Results indicate that while the UF-1000i could reduce the number of cultures needed—46% reduction for Group 1 and 57.5% for Group 2—the prevalence of false negatives raises concerns about its reliability, depending on patient characteristics and how positive cultures are classified.